Tag Archives: hypoxic ischemic encephalopathy

Cooling plus inhaled xenon for newborns with hypoxic-ischaemic encephalopathy

A new Cochrane Systematic Review has been published on how does cooling plus inhaled xenon compare with cooling alone for improving survival and development of newborn babies who may have suffered from lack of oxygen at birth? The Review has … Continue reading

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Cooling plus inhaled xenon for newborns with hypoxic-ischaemic encephalopathy

A new Cochrane Systematic Review has found that “Current evidence from one small randomised controlled pilot trial is inadequate to show whether cooling plus xenon is safe or effective in near-term and term newborns with HIE. Further trials reporting long-term … Continue reading

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Biochemical and clinical predictors of hypoxic–ischemic encephalopathy after perinatal asphyxia

Abstract Objective: To determine the usefulness of measures, available shortly after birth, as predictors of hypoxic–ischemic encephalopathy (HIE) following perinatal asphyxia. Patients: All inborn patients at Southmead Hospital between January 2012 and March 2014 at ≥36 weeks gestation with a … Continue reading

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Neonatal outcomes after introduction of a national intrapartum fetal surveillance education program: a retrospective cohort study

Abstract Objective: To determine the impact of a multidisciplinary fetal surveillance education program (FSEP) on term neonatal outcomes. Methods: A retrospective cohort study of term neonatal outcomes before (1998–2004) and after (2005–2010) introduction of a FSEP. Clinical data was collected … Continue reading

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The value of serum pro-oxidant/antioxidant balance in the assessment of asphyxia in term neonates

Abstract Objective: Asphyxia is a major cause of disabilities in term-born infants. Here we have explored the value in HIE (hypoxic-ischemic-encephalopathy) of using a combination of serum pro-oxidant/antioxidant balance (PAB) assay for predicting the prognosis of asphyxia. Method: Ninety term … Continue reading

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Preventing Pressure Injuries in Neonates Undergoing Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy: An Interprofessional Quality Improvement Project

Hospital-acquired pressure injuries (HAPIs) can be caused by multiple factors including pressure, shear, friction, moisture/incontinence, device-related pressure, immobility, inactivity, and nutritional deficits. Along with immobility, medical device-related (MDR) HAPIs are a primary cause of pressure injury in neonates, as the … Continue reading

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Changes in lactate dehydrogenase are associated with central gray matter lesions in newborns with hypoxic-ischemic encephalopathy

Abstract Purpose: Biomarkers may predict neurological prognosis in infants with hypoxic-ischemic encephalopathy (HIE). We evaluated the relationship between serum lactate dehydrogenase (LDH) and brain magnetic resonance imaging (MRI), which predicts neurodevelopmental outcomes, in order to assess whether LDH levels are … Continue reading

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