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Monthly Archives: September 2019
New ACOG guidelines for preventing early-onset group B streptococcus infection in newborns
The American College of Obstetricians and Gynecologists (ACOG) has released guidelines for prevention of early-onset group B streptococcus (GBS) infection in newborns, updating and replacing the obstetric portions of the 2010 guidelines from the Centers for Disease Control and Prevention … Continue reading
Neonatal death rates remain stagnant for third year in row
Bliss has raised its concerns that neonatal mortality rates in England and Wales remain almost unchanged for the third consecutive year. This follows the latest report to be published in August by the Office of National Statistics (ONS) on ‘Deaths registered … Continue reading
Management of Late Preterm and Term Neonates exposed to maternal Chorioamnionitis
Chorioamnionitis is a significant risk factor for early-onset neonatal sepsis. However, empiric antibiotic treatment is unnecessary for most asymptomatic newborns exposed to maternal chorioamnionitis (MC). The purpose of this study was to report the outcomes of asymptomatic neonates ≥35 weeks gestational … Continue reading
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Tagged antibiotics, chorioamnionitis, complete blood cell counts, Sepsis
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Comparison of NIV-NAVA and NCPAP in facilitating extubation for very preterm infants
Various types of noninvasive respiratory modalities that lead to successful extubation in preterm infants have been explored. The study aimed to compare noninvasive neurally adjusted ventilatory assist (NIV-NAVA) and nasal continuous positive airway pressure (NCPAP) for the postextubation stabilization of … Continue reading
Optimizing gentamicin conventional and extended interval dosing in neonates using Monte Carlo simulation – a retrospective study
Although aminoglycosides are routinely used in neonates, controversy exists regarding empiric dosing regimens. The objectives of this study were to determine gentamicin pharmacokinetics in neonates, and develop initial mg/kg dosing recommendations that optimized target peak and trough concentration attainment for … Continue reading