Tag Archives: antibiotics

Dynamics of the bacterial gut microbiota in preterm and term infants after intravenous amoxicillin/ceftazidime treatment

It is important to understand the consequences of pre-emptive antibiotic treatment in neonates, as disturbances in microbiota development during this key developmental time window might affect early and later life health outcomes. Despite increasing knowledge regarding the detrimental effect of … Continue reading

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Implementation of the Neonatal Sepsis Calculator in Early-Onset Sepsis and Maternal Chorioamnionitis

Utilization of the neonatal sepsis calculator published by Kaiser Permanente is rapidly increasing. This freely available online tool can be used in assessment of early-onset sepsis (EOS) in newborns 34 weeks’ gestation or more based on maternal risk factors and … Continue reading

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Management of Late Preterm and Term Neonates exposed to maternal Chorioamnionitis

Chorioamnionitis is a significant risk factor for early-onset neonatal sepsis. However, empiric antibiotic treatment is unnecessary for most asymptomatic newborns exposed to maternal chorioamnionitis (MC). The purpose of this study was to report the outcomes of asymptomatic neonates ≥35 weeks gestational … Continue reading

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Golden Hour Protocol for Preterm Infants A Quality Improvement Project

Preterm infants are a vulnerable patient population, especially during the first hours of life. Hypothermia, hypoglycemia, and early-onset sepsis are common problems related to prematurity. Implementation of a Golden Hour protocol has been shown to improve outcomes for preterm infants. This study evaluates the effectiveness … Continue reading

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Antibiotics, lung problems and death

In this study Dustin D. Flannery, from the University of Pennsylvania, led a team of researchers looking into the links between antibiotic use and increased risks of lung problems and death. 4,950 babies were involved in the study of whom … Continue reading

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Reducing antibiotic use in premature babies

In this study Ramachandra Bhat, from the University of South Alabama, led a team of researchers trying to reduce antibiotic use in premature babies. They developed and implemented guidance algorithms for the evaluation and management of suspected sepsis including measures … Continue reading

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Mice, gut bacteria and lung disease

Could the bacteria sometime used preventatively before women have Caesarean sections contribute to people developing lung problems? Recently scientists have become increasingly interested in the biome – the bacteria that live in and alongside people. A study on mice at Cincinatti … Continue reading

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