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Tag Archives: antibiotics
Antibiotic regimens for late‐onset neonatal sepsis
A new Cochrane Systematic review has concluded the “current evidence is insufficient to support any antibiotic regimen being superior to another. RCTs assessing different antibiotic regimens in late‐onset neonatal sepsis with low risks of bias are warranted.” To access the … Continue reading
Antibiotic regimens for early‐onset neonatal sepsis
A new Cochrane Systematic Review has found that the “current evidence is insufficient to support any antibiotic regimen being superior to another. Large RCTs assessing different antibiotic regimens in early‐onset neonatal sepsis with low risk of bias are warranted. To … Continue reading
C-reactive protein- and clinical symptoms-guided strategy in term neonates with early-onset sepsis reduced antibiotic use and hospital stay: a quality improvement initiative
Early-onset sepsis (EOS) is a potentially life-threatening complication of birth. Clinical symptoms are often unspecific and biomarkers have low predictive values for EOS. Therefore, clinical suspicion often leads to antibiotic therapy in neonates with a negative blood culture. In the … Continue reading
Posted in Uncategorized
Tagged antibiotics, C-reactive protein ratio, early onset sepsis, quality improvement
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Suspected neonatal sepsis: tenth clinical consensus of the Ibero-American Society of Neonatology (SIBEN)
Suspected neonatal sepsis is one of the most common diagnoses made in newborns (NBs), but very few NBs actually have sepsis. There is no international consensus to clearly define suspected neonatal sepsis, but each time that this suspected diagnosis is … Continue reading
Posted in Uncategorized
Tagged antibiotics, Diagnosis, laboratory testing, misdiagnosis, neonatal sepsis, Newborns
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Dynamics of the bacterial gut microbiota in preterm and term infants after intravenous amoxicillin/ceftazidime treatment
It is important to understand the consequences of pre-emptive antibiotic treatment in neonates, as disturbances in microbiota development during this key developmental time window might affect early and later life health outcomes. Despite increasing knowledge regarding the detrimental effect of … Continue reading