Monthly Archives: November 2019

Rapidly maturing fentanyl clearance in preterm neonates

Fentanyl is frequently used off-label in preterm newborns. Due to very limited pharmacokinetic and pharmacodynamic data, fentanyl dosing is mostly based on bodyweight. This study describes the maturation of the pharmacokinetics in preterm neonates born before 32 weeks of gestation. … Continue reading

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Neuroimaging findings in newborns with congenital heart disease prior to surgery: an observational study

Neurodevelopmental impairment has become the most important comorbidity in infants with congenital heart disease (CHD). This study aimed to investigate the burden of brain lesions in infants with CHD prior to surgery and explore clinical factors associated with injury. Abstract … Continue reading

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Problems of feeding, sleeping and excessive crying in infancy: a general population study

The aim of this study was to study regulatory problems (RPs) of feeding sleeping and excessive crying in infancy, and explore the influence of maternal mental health problems and parent–child relationship problems. Abstract available in Archives of Disease in Childhood, … Continue reading

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Morbidity and mortality in patients with persistent pulmonary hypertension of the newborn

In a recent, population-based study of infants >34 weeks of gestational age with a diagnosis of persistent pulmonary hypertension of the newborn (PPHN), who were treated in California, the discharge mortality during birth hospitalization was 6.5 percent and one-year post-discharge … Continue reading

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Respiratory monitors to teach newborn facemask ventilation: a randomised trial

This study looks to determine if whether using a respiratory function monitor (RFM) during mask ventilation training with a manikin reduces facemask leak. Available in BMJ ADC Fetal & Neonatal edition, November 2019, Vol. 104 Iss. 6 (subscription and log in … Continue reading

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