Does indomethacin do any good?

Indomethacin is a non-steroidal anti-inflammatory drug sometimes given – for preventative (prophylactic) purposes – to extremely premature babies. In this study the medical records of 671 babies were analysed. 141 had not been given indomethacin while the rest had. The study found that the babies who had been given indomethacin were less likely to die, and were less likely to develop lung problems. However, there was no significant effect of prophylactic indomethacin on the incidence of severe intra-ventricular haemorrhage or patent ductus arteriosus ligation.

You can read the abstract of this article here.


About John Gale

I work as a medical librarian in the Joint Education and Training (JET) library at Leighton Hospital, Crewe. I keep clinicians up to date with the latest research, help them to find the best information about treatment and train them to find - and assess - high-quality information for themselves. I also help doctors and nurses find and write high-quality information for patients.
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