Corticosteroid therapy and neonatal septic shock

Babies sometimes suffer blood infections after they are born which can lead to the development of septic shock. One of the ways used to treat this condition is drugs called corticosteroids and in this article Gabriel Altit, from the Universite de Montreal, led a team of researchers looking into their effectiveness. The team analysed the treatment records of 62 babies. 39 had been given drugs called inotropes and hydrocortisone while the rest had only been given inotropes. Despite receiving more inotropes (meaning their condition was worse), being more premature and more frequently suffering from necrotising enterocolitis the babies who had been given hydrocortisone had similar survival rates. However, the babies who had been given hydrocortisone were “less likely to survive at their 1-year postmenstrual age follow-up when accounted for gestational age at birth and duration of inotropes.”

You can read the abstract of this article here.


About John Gale

I work as a medical librarian in the Joint Education and Training (JET) library at Leighton Hospital, Crewe. I keep clinicians up to date with the latest research, help them to find the best information about treatment and train them to find - and assess - high-quality information for themselves. I also help doctors and nurses find and write high-quality information for patients.
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