Down’s syndrome and necrotising enterocolitis

Necrotising enterocolitis is a condition in which bacterial infection causes cells in parts of babies bowels to die off. In this study Clifford L. Cua, from the Nationwide Children’s Hospital in Columbus, Ohio, led a team of researchers looking into the links between Down’s syndrome and an increased risk of developing necrotising enterocolitis. The study found that the incidence of necrotising enterocolitis in new-born babies with Down’s syndrome was 6.6%. Babies with Down’s Syndrome were more likely to be born earlier, have a diagnosis of congenital diaphragmatic hernia, ventricular septal defect, patent ductus arteriosus, Ebstein’s anomaly and left-sided obstructive lesions. Babies with Down’s syndrome and necrotising enterocolitis were two-and-a-half times more likely to die than babies without Down’s syndrome who had necrotising enterocolitis.

You can read the abstract of this article here.


About John Gale

I work as a medical librarian in the Joint Education and Training (JET) library at Leighton Hospital, Crewe. I keep clinicians up to date with the latest research, help them to find the best information about treatment and train them to find - and assess - high-quality information for themselves. I also help doctors and nurses find and write high-quality information for patients.
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