Is High-Flow Nasal Cannula Noninferior to Nasal CPAP for the Initial Management of Preterm Infants?

Effective ventilatory support is essential to the survival of extremely preterm infants in the NICU; however, much is still unknown regarding avoidance of treatment failure and progression to invasive mechanical ventilation. This randomized trial assessed the effectiveness of high flow nasal cannula versus nasal CPAP among infants >28 weeks’ gestational age with early RDS, and found an increase in treatment failure among infants receiving high flow nasal cannula.

To read more from Evidence-Based Neonatology click here.

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