Effectiveness of Delayed Cord Clamping in Reducing Postdelivery Complications in Preterm Infants: A Systematic Review

Cord clamping can be used in preterm infants to reduce the following complications:

  • Anaemia
  • Hemodynamic instability
  • Development of intraventricular haemorrhages

This systematic review evaluates the evidence on the effectiveness of delayed cord clamping in reducing these complications.

There are a number of interventions including:

  • Varying durations of delayed cord clamping with and without cord milking as compared with immediate cord clamping
  • Shorter delays in cord clamping
  • Delayed cord clamping without cord milking

A comprehensive search of randomized controlled trials, observational, cohort, and before-after studies was conducted between 1946 and 2015.

The outcome measures listed below were included:

  • Hematocrit/hemoglobin levels,
  • Measured or calculated blood volumes levels
  • Number and volume of blood transfusions
  • Presence of hypotension and need for treatment
  • Development of intraventricular haemorrhage

Delayed cord clamping can lead to improved outcomes measures in preterm infants. The current recommendation to support delayed cord clamping in preterm infants is supported by the review.

The full abstract can be accessed here

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